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• GHK-Cu occurs naturally in human plasma but its concentration declines dramatically with age, dropping from approximately 200 ng/mL at age 20 to about 80 ng/mL by age 60

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If you have additional risk factors (PCOS with 50% lower glutathione, IVF with 70-83% depleted antioxidants, gallbladder issues, choline deficiency), your effective "safe" dose may be significantly lower